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The Significance of Bleeding after the Menopause

Bleeding after the menopause or "post-menopausal bleeding" ("PMB") can be defined as the resumption of vaginal bleeding at least 6 months after a woman experiences her last menstrual period. This assumes of course that she is indeed menopausal ie. in her late 40's, perhaps having hot flashes and night sweats, mood swings, insomnia, perhaps experiencing some vaginal dryness. The bleeding pattern most women experience as they approach menopause is one where the periods become lighter, shorter in duration, and the interval between periods changes so that the periods are either somewhat closer together (between 21-26 days apart) or intervals greater than her customary 28 days. Cycles may be missed entirely for a couple of months.
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There are many causes of postmenopausal bleeding, and the most common is hormone replacement therapy. Women who are taking hormone replacement therapy very often may develop PMB because the uterine lining is very sensitive to estrogen, which promotes growth of the endometrium, just as it does in the normal reproductive cycle that was operative prior to menopause. Lack of estrogen, on the other hand, may cause atrophy of the lining, and in this condition, the blood vessels of the uterine lining become so fragile because of estrogen lack that they spontaneously break and then bleed.

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